Popular P&O Cruises from Southampton

Looking ahead to your next big adventure? A P&O cruise from Southampton awaits.

Find our fantastic range of handpicked P&O cruises from Southampton below. Plus, book today & earn Cruise Miles®.

Why Choose P&O Cruises?

Sailing with P&O Cruises is all about choice, comfort and value.

The cruise lines' modern fleet, including favourites like Arvia and Iona, combines British style with innovative features, giving you a home-from-home at sea.

You’ll enjoy full-board dining, world-class entertainment and activities designed for every type of traveller, whether you’re seeking family fun, a romantic escape, or a grown-ups-only retreat.

Why Cruise from Southampton?

Southampton is the UK’s busiest cruise port, offering hassle-free departures and a wide choice of sailings with P&O Cruises.

Whether you’re heading to the sunny Mediterranean, exploring the Norwegian Fjords, or venturing further afield to the Caribbean, sailing from Southampton means your holiday begins the moment you arrive at the port.

Why Book with ROL Cruise?

When you book your P&O cruise from Southampton with ROL Cruise, you can relax knowing you’re in safe hands. We’re ABTA and ATOL protected, and proud to be the UK’s No.1 Independent Cruise Specialist. Over the past decade, we’ve picked up more than 50 industry awards, but what really sets us apart is our team. With over 1,000 years of combined experience - and plenty of us having sailed with P&O Cruises from Southampton ourselves - you’ll always get genuine, first-hand advice tailored just for you.

And the perks don’t stop there. Every pound you spend earns you a Cruise Mile through our exclusive Cruise Miles® programme, which has already helped our customers save over £12 million on their holidays. You’ll also collect P&O Cruises’ The Peninsular Club points along the way, so your next cruise is even more rewarding.